Using polyphenolic extract for tubers Cyperus rotundus to prevent myocardial infarction

Authors

  • Mohammed A. Auda 1Department of Chemistry, College of Science, Thi-Qar University, Iraq
  • Alyaa Majid 1Department of Chemistry, College of Science, Thi-Qar University, Iraq
  • Khalid G. Al-Fartosi2 G. Al-Fartosi National University of Science and Technology, Iraq

DOI:

https://doi.org/10.32792/jeps.v11i2.121

Keywords:

Cyperus rotundus, Myocardial infarction, cardiac markers, polyphenol

Abstract

The present study aimed at determining the effect polyphenolic extract for tubers cyperus rotundus on myocardial infarction in female rats. In this study, 36 female rats were used and the animals were divided into 6 groups of each group containing (6 rats). Myocardial infarction was induced by injection of isoproterenol at (85 mg/kg) in the intraperitoneally of female rats at an interval of 24 h for two days. The results showed that the injection of isoproterenol in the intraperitoneally of female rats has caused a significant increase in levels of Troponin-I, lactate dehydrogenase(LDH), creatine phosphokinase (CPK), alanine transferase (ALT), aspartic transferase (AST) and necrosis in the second group compared to the first group. It was found in the current study that treatment of female rats with myocardial infarction with phenolic extract of tubers of cyperus rotundus has caused a significant decrease in levels of Troponin-I, lactate dehydrogenase (LDH), creatine phosphokinase (CPK), alanine transferase (ALT), aspartic transferase (AST). Necrosis decreased in the group treated with phenolic extract of tubers of cyperus rotundus. From this we conclude that the phenolic extract of cyperus rotundus of tubers has protective role against myocardial infarction

References

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Published

2022-04-07

Issue

Vol. 11 No. 2 (2021): Journal of Education for Pure Science- University of Thi-Qar

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