Study of Antifungi activity and bioactive Compounds of brown alga extract

Authors

  • Department of Biology College of Education for Pure Science,University of Thi-Qar, Thi-Qar 64001,
  • Department of Biology College of Education for Pure Science,University of Thi-Qar, Thi-Qar 64001

DOI:

https://doi.org/10.32792/jeps.v13i1.240

Keywords:

Bioactive compounds, Laminaria, antifungi, Gc-mass.

Abstract

The objective of this study was to determine bioactive compounds and antifungi of extracts of
Laminaria sp. against pathological fungi, which are Aspergillusniger, Candida albicans , and Candida
krusei, as the effective compounds extracted from this algae solvents were used (hot water and ethanol
alcohol) and the products of secondary metabolism from the aqueous extract were qualitatively detected,
which indicates existence of chemical compounds such as flavonoids and phenols Glycosides, terpenes
and carotenoids, Identified chemical compounds in the ethanolic extract of seaweed using gas
chromatography-mass spectrometry (Gc-mass). These compounds were Oleic acid, n-Hexadecanoic acid
, Fucosterol , Cyclohexane, 1,5-diethenyl-3-methyl-2-methylene-, (1.alpha.,3.alpha.,5.alpha.)- ,
Tetradecanoic acid and D-Mannitol. The aqueous extract of Laminaria sp. did not appear any biological
activity versus all the studied fungal species. While the ethanolic extract was found to be more effective
in its effect on pathogenic fungal species. The average zones of inhibition of the extract were (21.53,
21.46, 20.00) against C.albicans , A.niger and C.krusei , respectively.

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Published

2023-04-04

Issue

Vol. 13 No. 1 (2023): Journal of Education for Pure Science- University of Thi-Qar

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