COVID-19 Vaccines and therapeutics
Abstract
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that first appeared in
Wuhan, China, gave rise to the coronavirus disease 2019 (COVID-19), a highly contagious and
pathogenic viral infection. COVID-19 is not currently being treated with a specific therapy. Remdesivir is
the first medication to be approved by the Food and Drug Administration (FDA) to treat COVID-19.
However, numerous alternative therapy modalities are being looked for as COVID-19 therapies. As part
of this review, we discussed the development of various drugs, their mechanism of action, and how they
might be applied to different cases of COVID-19 patients. This review also offers an update on the
development of novel COVID-19 preventive or therapeutic vaccines. We aimed to include the most
recent published data from phase III trials about various COVID-19 vaccines and include clinical data
made available on networks or peer-reviewed journals in addition to vaccines approved by the Food and
Drug Administration (FDA) or The World Health Organization (WHO).
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