Evaluation of IL-1α and IL-10 Asociation with Acne In The Province of Thi-Qar
Keywords:Acne vulgaris, IL-1α, IL-10.
AbstractThis study was conducted in the labs of the College of Education for Pure Sciences, Al-Hussein Educational Hospital and Al-Nahrain Specialized Laboratory of the Health Department of Thi-Qar province, during the period from October 2018 to March 2019. The study included of 100 blood sample of patients with acne (39 males) and (61 females) and their age between 10-35 years. The patients were divided into groups according to age stages to three age groups. The age group 10-20 years is the most prevalent group 52/100 (52%). Followed by patients group 21-30 years was 42/100 (42%) and patients group more than 31years was 6/100 (6%). Blood serum was isolated by using centrifuge and examination was performed by using ELISA technique.
The current study showed detection of the level of some cytokines and their relationship to acne vulgaris, where included measuring the concentration of interleukins in the blood of persons with acne and comparing them with healthy persons including interleukin-1α and interleukin-10.
The results of the statistical analysis showed a high significant increase (p <0.05) in patients with acne in concentration of the (IL-1α) and (IL-10), where they were examined for 70 samples of acne patients, and 20 healthy samples in the control group. The results showed a significant increase (P<0.05) in the levels of interleukins in the serum (IL-1α, IL-10) in all acne patients compared to control group.
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