Effect of gum Arabic and arginine on antioxidant activity and the growth of Lactobacillus in rats

Authors

  • Department of Biology, Collage of Education for pure Science, University of Thi-Qar, 64001, Iraq
  • Department of Biology, Collage of Education for pure Science, University of Thi-Qar, 64001, Iraq
  • Department of Biology, Collage of Education for pure Science, University of Thi-Qar, 64001, Iraq

Abstract

The aim of this study was to determine the antioxidant activities and their effect on the numbers of
Lactobacillus of dietary gum arabic and arginine supplemented in female rat. In this study, the common test
for measuring antioxidant activity of the plasma was evaluated using 2, 2-diphenyl-l-picrylhydrazyl assay
(DPPH. The active compounds were detected using GC-mass and the Lactobacillus bacteria was evaluated
by detecting them in the MRS culture medium, agar. The results showed that there were significant
differences between the studied groups, where the highest (87.00 ± 2.00) rate of antioxidants was recorded in
the group of gum Arabic and arginine, while the lowest (40.67 ± 2.51) percentage was recorded in the
positive control group. The results of GC-mass also showed the presence of many active compounds in the
extract of Arabic gum that act as antioxidants, microorganisms, allergens, and anti-cancer. The GA + AA
group also recorded the highest average number of Lactobacillus bacteria (240.66) compared to the rest of
the other groups. These findings support the notion that the gum arabic a good source of bioactive
compounds. From the study it was observed that there was a significantly increased (p ≤ 0.05) in plasma
total antioxidant capacity and increase the growth of Lactobacillus in rat after the consumption of gum
arabic and arginine.

References

- Said, A.M., Atwa, S.A.E. & Khalifa, O.A. Ameliorating effect of gum arabic and lemongrass on

chronic kidney disease induced experimentally in rats. Bull Natl Res Cent 43, 47 (2019).

https://doi.org/10.1186/s42269-019-0086-x

- Zeid, I. M. A., & FarajAllah, A. R. (2018). Gum Arabic and Kidney Failure: A Exceptional Panacea. In

Gum Arabic (pp. 245-260).

- Nasir, O. (2014). Effect of gum Arabic (Acacia Senegal) on glucose metabolism body weight gain

in mice. Journal of Biology. 4- 9 ; 34.

- Ali BH, Ziada A, Blunden G.(2009). Biological effects of gum arabic: a review of some recent

research. Food Chem Toxicol. (2009) 47:1–8. Doi.

- Gamal el-din AM, Mostafa AM, Al-Shabanah OA, Al-Bekairi AM, Nagi MN. Protective effect of arabic

gum against acetaminophen-induced hepatotoxicity in mice. Pharmacol Res. 2003 Dec;48(6):631-635.

- Abd-El-Hafez SM, Ismael AB, Soliman MM, Mohamed EH, Kafaween IK, Mohamed HH. Effect of

gum arabic and Nigella sativa on T-helper1 and T-helper2 immune response in Wistar rats infected with

methicillin-resistant Staphylococcus aureus. Natl J Physiol Pharm Pharmacol 2017;7(12): 1410-1416.

-Roberfroid, M., Gibson, G., Hoyles, L., McCartney, A., Rastall, R., Rowland, I., . . . Meheust, A. (2010).

Prebiotic effects: Metabolic and health benefits. British Journal of Nutrition, 104(S2), S1-S63.

doi:10.1017/S0007114510003363

- Nakov, G.; Georgieva, D.; Ivanova, N.; Damyanova, S Stamatovska, V.; Necinova, L. Prebiotic e

Downloads

Published

2023-11-04