Study Effect Hormone Doping (Growth Horemone Releasing Hexo- Peptids(GHRP- (6) and Insuline of Cholesterol, Triglycerides, High and Low Density Lipoprotein to Laboratory Rats
DOI:
https://doi.org/10.32792/jeps.v10i1.38Keywords:
GHRP-6, nsuline, cholesterol, VLDL, HDL, T.GAbstract
The study showed the effect of hormonal activity GHRP-6 and insulin used in laboratory animals by 48males and 48 females divided into six groups. The control group was injected with a 0.1 mg solution and
the other groups were injected with a mixture of stimulants at 0.01and 0.01 times syringe (P <0.05) in the
first group of males and in the female treatment groups, and a significant increase in the complex
triglycerides excluding the group (P <0.05) and both sexes were observed, (P <0.05) was significantly
higher in proteins VLDL and HDL in male rats and significantly lower in fameles (P <0.05), significant
increase (P <0.05), was significantly higher in Cholesterol in the male rats and significant decrease in
fameles (P <0.05) treated with a combination of stimulants (GHRP-6 + Insulin) compared with control
group.
References
-١(JADO) المنظمة الأردنیة لمكافحة تعاطي المنشطات النسخة ألاولى .عمان.المملكة الاردنیة .. ( ٢٠٠٨ ). قواعد تعاطي المنشطات
. الھاشمیة .ص ١٦٣
٢- المنظمة غرب أسیا لمكافحة المنشطات ،( ٢٠٠٩ ).الدلیل المرشد اللاعبین التثقیفي لمكافحة المنشطات الوكالة العالمیة لمكافحة
. المنشطات بتعاون مع المجلس الاولمبي الاسیوي والمنظمة الاردنیة لمكافحة المنشطات،النسخة الاولى .طبعة الخامسة .ص ٩
-Hersch, E.C. & Merriam, G.R. (2008). Growth hormone (GH)-releasing hormone and GH
secretagogues in normal aging: Fountain of Youth or Pool of Tantalus? Clin Interv Aging 3, 121-9.
-Cabrales, A. Gil, J. Fernández, E. Valenzuela, C. Hernández, F. García, I. Hernández, A. Besada,
V. Reyes, O. Padrón, G. Berlanga, J. Guillén, G. González, LJ. (2013). Eur J Pharm Sci. 48 (1–2): 40-
-Grapengiesser E, Hellman B, Gylfe E, Dansk H, Salehi A; Gylfe; Dansk; Salehi (2007): Insulin
oscillations--clinically important rhythm. Anti-diabetics should increase the pulsative component of the
insulin release. Lakartidningen (in Swedish) 104 (32–33): 2236–9.
-Kafrouni, M. I.; Anders, R. A. and Verma, S. (2007). Hepatotoxicity associated with dietary
supplements containing anabolic steroids. Clin. Gastroenterol. Hepatol. 5(7): 809-812.
-Tietz, N.W. (1999). Text book of clinical chemistry. 3rd Ed. C.A. Burtis, E. R. Ashwood, W. B.
Saunders. Pp: 819- 861.
-Trinder, P. (1969). Ann. Clin. Biochem. (6) Pp : 27-29.
-Allain, C. C., Poon, L. S., Chan, C. S., Richmond, W. & Fu, P. C. (1974). Enzymatic determination of
total serum cholesterol. Clin. Chem. 20(4), 470 - 475.
-Koren, D. (1955). Clearing Factors: a heparin activated Lipoprotein Lipase. Isolation and
characterization of enzyme from normal rats. J. Biol. Chem., 215(1) Pp: 1-14.
-Saher Mahmood Jwad& Doaa Yousif Mohamme. (2017). Effect of Some Types of Doping Used
by Athletes on Liver andKidneys Functional Performance in Albino Male Rats. Journal of Global
Pharma Technology. ISSN: 0975 -8542.
-Ralf Nass, M.D., Suzan, S. Pezzoli, B.A., Mary Clancy Oliveri, M.S. James, T. Patrie, M.S.,
Frank E. Harrell Jr, Jody L. Clasey, Steven, B. Heymsfield, M.D. Mark, A. Bach, M.D. Mary Lee
Vance, M.D. Michael, O. Thorner, M.B. B.S. D.Sc. (2008). Effects of an Oral Ghrelin Mimetic on
Body Composition and Clinical Outcomes in Healthy Older Adults: A Randomized, Controlled Trial.
Published in final edited form as:4; 149(9): 601–611.
-Garevik, N.; Skogastierna, C.; Rane, A. and Ekstrom, L. (2012). Single dose testosterone increases
total cholesterol levels and induces the expression of HMG CoA reductase. Substance Abuse Treatment
Prev. Policy. 7(12): 1-6.)
-Kafrouni, M. I.; Anders, R. A. and Verma, S. (2007). Hepatotoxicity associated with dietary
supplements containing anabolic steroids. Clin. Gastroenterol. Hepatol. 5(7): 809-812.
-Elder, K. & Steng, G. (2000). Plasma thyroxin and cholesterol concentration miniature pigs are
influenced by thermally oxidized dietary lipids.J. Nutr., 130pp: 116-121.
-Horowitz, J. F. (2003). Fatty acid mobilization from adipose tissue during exercise. TRENDS in
Endocrinol. Metabol. 14(8): 386-392.
and, Sakata, T. (2004). Role of fatty acid composition in the development of metabolic disorders in
sucrose-induced obese rats. Exp. Biol. Med. (Maywood) 229, 486–493.
- Kraegen, EW., Cooney ,GJ. Ye, J.Thompson, AL.(2001). Triglycerides, fatty acids and insulin
resistance--hyperinsulinemia.Exp Clin EndocrinDiabetes. ;109(4):S516-26.
-Yakubu, M.T.; Akanji, M.A. and Oladiji, A.T. (2005). A phrodisiac potentials of the aqueous
extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male albino rats. Asian Journal of Andrology 7
(4) Pp : 399-404.
-Barnard, R. (2012). Body composition and measurements of elite senior South African body builders
during a competitive season. Thesis, University of the Free State.
-Morikawa, A. T.; Maranhao, R. C.; Alves, M. N.; Negrao, C. E.; Silva, J. L. and Vinagre, C.G.
(2012). Effects of anabolic androgenic on chylomicron metabolism. Steroids 77(13): 1321-1326.)
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