Relationship of Some Biomarkers and the Risk of Autoimmune Hypothyroidism (Hashimoto’s) Among the Population in Thi-Qar Governorate

Abstract

  This study was designed to determine the prevalence of autoimmune hypothyroidism (Hashimoto's) and its impact on men and women in Thi-Qar  Governorat  .The current study included (100) people who were in two groups, with (50) people in each group. The first group includes patients with hypothyroidism (Hashimoto's), and the second group includes (Healthy) people who do not suffer from any thyroid disease.  Blood samples were collected for the period from (January 1 to March 30/ 2023), for use in measuring the level of thyroid hormones and measuring the level of autoantibodies.

    The results of the current study showed that female patients had the highest incidence of autoimmune hypothyroidism (Hashimoto’s),  at a rate of (68%), while for males, the incidence rate was (32%). As for the age group, the highest incidence rate was for ages over 40 years, and in both cases of the disease

    The results also showed a relationship between (Sex, Family History, Smoking) and the risk of developing autoimmune hypothyroidism (Hashimoto’s).   The results of the current study also showed an increase in the average concentration of thyroid-stimulating hormone (TSH) in patients with hypothyroidism (Hashimoto’s), corresponding to a decrease in the average concentration of each of the hormones (T3, T4, FT4) compared to the healthy group. An increase in the level of autoantibodies (Anti-TPOAb, Anti-TgAb) was also observed in patients compared to healthy people.