The Vitamin D and Autoimmune Thyroiditis: A Systematic Review to Establish a Clinical Immunological Relationship: Vitamin D and Autoimmune Thyroiditis

Zainab  Kadm; Prof. Dr Hind mizhur mousa

doi:10.32792/jeps.v15i4.731

المؤلفون

Zainab Kadm University of Thi-Qar college of silences https://orcid.org/0009-0005-8983-8954
Prof. Dr Hind mizhur mousa Thi-qar university

DOI:

https://doi.org/10.32792/jeps.v15i4.731

الكلمات المفتاحية:

Autoimmune thyroiditis , Hypothyroidism , Vitamin D

الملخص

Autoimmune thyroiditis is a class of thyroid gland illnesses defined by aberrant lymphocyte activity directed against self-tissues and is mostly represented by HT and GD, affecting roughly 2% to 3% of the population with a female predominance. It is yet unknown the etiopathogenesis of autoimmune thyroiditis. However, many environmental elements are well-known to raise the risk of developing AIT in addition to genetic and epigenetic factors. Besides its conventional function in bone health, the pleiotropic properties and widespread receptor expression of vitamin D have proven benefits in many different systems. To gain a better grasp of the effects of serum 25(OH)D in thyroid disease, we sought to compile and summarize the knowledge concerning the vitamin D impact on AITD by means of a search of papers included in electronic databases (PubMed, Google Scholar, CrossRef) from September to December 2024. The abundance of evidence supported the findings, which suggested that lack of vitamin D significantly correlated with an elevated danger of contracting or having autoimmune thyroiditis, as well as an inverse association between serum 25(OH)D concentration and anti-thyroid antibody titers. Knowing risk factors helps one to modify their food and lifestyle to lower the risk of developing the disease and mitigate the course of autoimmune thyroiditis

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